Modeling HIV quasispecies evolutionary dynamics
نویسندگان
چکیده
منابع مشابه
Modeling Evolutionary Dynamics of HIV Infection
During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively). The switch in coreceptor usage has been correlated with a faster progression of the disease to the AIDS phase. As several pharmaceutical companies are starting large phase III trials for R5 and X4 drugs,...
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ژورنال
عنوان ژورنال: BMC Evolutionary Biology
سال: 2007
ISSN: 1471-2148
DOI: 10.1186/1471-2148-7-s2-s5